A modular designed copolymer with anti-thrombotic activity and imaging capability.

نویسندگان

  • Nan Xie
  • Ke Feng
  • Bin Chen
  • Ming Zhao
  • Li-Ping Zhang
  • Chen-Ho Tung
  • Li-Zhu Wu
  • Shiqi Peng
چکیده

Through a modular ROMP (ring-opening metathesis polymerization) strategy, a random copolymer with anti-thrombotic activity and imaging capability has been constructed from RGD, rhodamine B and PEG modified norbornene monomers. As we expected, these tri-component polynorbornenes exhibit significant enhancement in anti-thrombotic efficacy and bioavailability in vivo.

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عنوان ژورنال:
  • Chemical communications

دوره 50 67  شماره 

صفحات  -

تاریخ انتشار 2014